Urease - Helicobacter pylori - NCBI Bookshelf
Urease represents an interesting model for metalloenzyme studies. Before the discovery of H. pylori, humans were thought to produce "gastric urease.'' It is now known that the source of this notable …
Helicobacter pylori urease for diagnosis of Helicobacter pylori ...
Sep 1, 2018 · Gastric urease allows the organism to colonize the acidic stomach and serves as a biomarker for the presence of H. pylori. Important clinical tests for H. pylori, the rapid urease test and …
Frontiers | The effect of three urease inhibitors on H. pylori ...
Nov 15, 2024 · H. pylori produces large quantities of urease (6–10% of the total protein) which converts urea into ammonia and carbamate, enabling the bacterium to survive in the acidic gastric …
New Directions in Helicobacter pylori Urease Inhibitors: Focusing on ...
Jun 17, 2025 · Although some natural products that inhibit urease maturation have shown good effects in inhibiting urease activity, their clinical application is still mainly for the treatment of other …
Anti-urease therapy: a targeted approach to mitigating antibiotic ...
May 28, 2025 · Urease enables the survival and colonization of H. pylori by neutralizing stomach acidity. Targeting this urease without disrupting beneficial gut microflora offers a selective mechanism to …
The effect of three urease inhibitors on H. pylori viability, urease ...
Nov 15, 2024 · We hypothesized that urease inhibition could affect H. pylori viability. This work aimed to assess the effects of acetohydroxamic acid (AHA), ebselen and baicalin on urease activity, bacterial …
Targeting Helicobacter pylori urease activity and maturation: In-cell ...
Oct 1, 2018 · To survive inside the very acidic environment of the gastric niche, H. pylori has created a unique adaptive mechanism relying on the Ni (II)-dependent enzyme urease, which catalyzes the …
Unveiling Novel Urease Inhibitors for Helicobacter pylori: A Multi ...
Feb 6, 2024 · Helicobacter pylori (Hp) infections pose a global health challenge demanding innovative therapeutic strategies by which to eradicate them. Urease, a key Hp virulence factor hydrolyzes urea, …
Unveiling Novel Urease Inhibitors for Helicobacter pylori: A Multi ...
Helicobacter pylori (Hp) infections pose a global health challenge demanding innovative therapeutic strategies by which to eradicate them. Urease, a key Hp virulence factor hydrolyzes urea, facilitating …
Helicobacter Pylori (H. Pylori) - Ohio Gastro
H. pylori sticks to your stomach lining and damages it. The bacteria makes an enzyme called urease that makes your stomach acid less acidic and can cause more acid production.