Pancytopenia (marked decreases in RBCs, neutrophils and platelets) and bone marrow suppression have been reported in the literature to occur within 3 to 7 weeks after the concomitant administration...

ADYNOVATE, Antihemophilic Factor (Recombinant), PEGylated, is formulated as a sterile, non-pyrogenic, white to off-white lyophilized powder for reconstitution for intravenous injection.

The FDA provides guidelines and information on Pegasys® (peginterferon alfa-2a) for medical use and treatment of chronic hepatitis C.

Oct 21, 2002 · Non-pegylated interferon alfa-2a treatment of pregnant Rhesus monkeys at approximately 20 to 500 times the human weekly dose resulted in a statistically significant increase …

Dec 31, 2002 · Non-pegylated interferon alfa-2a treatment of pregnant Rhesus monkeys at approximately 20 to 500 times the human weekly dose resulted in a statistically significant increase …

Oct 3, 2001 · The specific activity of pegylated interferon alfa-2b is approximately 0.7 x 10 8 IU/mg protein. Interferon alfa-2b, is a water-soluble protein with a molecular weight of 19,271 daltons …

Rx only Alpha interferons, including PEGASYS (peginterferon alfa-2a), may cause or aggravate fatal or life-threatening neuropsychiatric, autoimmune, ischemic, and infectious disorders. Patients should be …

The effects of pegylated interferon alfa-2b on the pharmacokinetics of drugs metabolized by cytochrome P-450 enzymes have not been studied at the higher clinical doses for patients with …

Tissues with the highest concentration of both pegylated and non-pegylated IFN -1a were spleen, kidney, liver, and lung; whereas, muscle, brain, and spinal cord had the lowest concentrations.

KRYSTEXXA® (pegloticase) is a PEGylated uric acid specific enzyme indicated for the treatment of chronic gout in adult patients refractory to conventional therapy.