Dyspepsia is the most common symptom in PUD, occurring in 80% to 90% of patients. 1,3,12 However, dyspepsia can occur in other diseases as well, causing these conditions to present similarly to PUD.

Patients older than age 55 years or those of any age with alarm features should undergo upper GI endoscopy first. 9 Endoscopy enables direct visualization of the mucosa and is the most sensitive and ...